PGK1 Antibody

• Background:

  Also known as ATP:3-phosphoglycerate 1-phosphotransferase, this major enzyme in glycolysis catalyzes the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate, generating one molecule of ATP. Phosphoglycerate kinase not only functions in glycolysis but is secreted by tumor cells and is proposed to participate in the angiogenic process as a disulfide reductase. Mutations in PGK1 may be associated with hemolytic anemia.

• NCBI Gene ID:

  5230

• Swiss Prot:

  P00558

• Accession Number:

  P00558

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PGK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-334 amino acids from the Central region of human PGK1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  45 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PGK1

• NCBI Official Name:

  Phosphoglycerate kinase 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Shetty, S., et al., Am. J. Respir. Cell Mol. Biol. 31 (1) :100-106 (2004) .

• Background Reference 02:

  Daly, E.B., et al., Biochim. Biophys. Acta 1691 (1) :17-22 (2004) .

• Background Reference 03:

  Daly, E.B., et al., Int. J. Biol. Markers 19 (2) :170-172 (2004) .

• Background Reference 04:

  Saito, Y., et al., Biochem. Biophys. Res. Commun. 314 (2) :396-402 (2004) .

• Other Product Names:

  Phosphoglycerate kinase 1, Cell migration-inducing gene 10 protein, Primer recognition protein 2, PRP 2, PGK1, PGKA

• Tested Applications:

  WB, IHC-P

• Protein ID:

  52788229

• Physical Properties:

  Liquid