MNK2 Antibody

• Background:

  MKNK2 may play a role in the response to environmental stress and cytokines. This protein appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.

• NCBI Gene ID:

  2872

• Swiss Prot:

  Q9HBH9

• Accession Number:

  Q9HBH9

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MNK2 (MKNK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-432 amino acids from the C-terminal region of human MNK2 (MKNK2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  52 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  MKNK2

• NCBI Official Name:

  MAP kinase-interacting serine/threonine-protein kinase 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Scheper, G.C., et al., Mol. Cell. Biol. 23 (16) :5692-5705 (2003) . Knauf, U., et al., Mol. Cell. Biol. 21 (16) :5500-5511 (2001) . Scheper, G.C., et al., Mol. Cell. Biol. 21 (3) :743-754 (2001) . Slentz-Kesler, K., et al., Genomics 69 (1) :63-71 (2000) . Haribabu, B., et al., Proc. Natl. Acad. Sci. U.S.A. 90 (20) :9398-9402 (1993) .

• Other Product Names:

  MAP kinase-interacting serine/threonine-protein kinase 2, MAP kinase signal-integrating kinase 2, MAPK signal-integrating kinase 2, Mnk2, MKNK2, GPRK7, MNK2

• Tested Applications:

  WB

• Protein ID:

  90102033

• Physical Properties:

  Liquid