PNCK Antibody

• Background:

  Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

• NCBI Gene ID:

  139728

• Swiss Prot:

  Q6P2M8

• Accession Number:

  Q6P2M8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PNCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the C-terminal region of human PNCK.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  39 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PNCK

• NCBI Official Name:

  Calcium/calmodulin-dependent protein kinase type 1B

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Gardner, H.P., et al., Cancer Res. 60 (19) :5571-5577 (2000) .

• Background Reference 02:

  Gardner, H.P., et al., Genomics. 63 (2) :279-288 (2000) .

• Other Product Names:

  Calcium/calmodulin-dependent protein kinase type 1B, CaM kinase I beta, CaM kinase IB, CaM-KI beta, CaMKI-beta, Pregnancy up-regulated non-ubiquitously-expressed CaM kinase, PNCK

• Tested Applications:

  WB, IHC-P

• Protein ID:

  67466915

• Physical Properties:

  Liquid