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ARGBP2 Antibody

CAT: 0223-62-578Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-578Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. ARGBP2 is the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton.
NCBI Gene ID
8470
Swiss Prot
O94875
Accession Number
O94875
Host
Rabbit
Reactivity
Human
Immunogen
This ARGBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-204 amino acids from the N-terminal region of human ARGBP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
124 kDa
Fragment
Rabbit Ig
Symbol
SORBS2
NCBI Official Name
Sorbin and SH3 domain-containing protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Yuan, Z.Q., et.al., J. Biol. Chem. 280 (22), 21483-21490 (2005)
Background Reference 02
Olsen, J.V., et.al., Cell 127 (3), 635-648 (2006)
Background Reference 03
Taieb, D., et.al., Cancer Res. 68 (12), 4588-4596 (2008)
Other Product Names
Sorbin and SH3 domain-containing protein 2, Arg/Abl-interacting protein 2, ArgBP2, Sorbin, SORBS2, ARGBP2, KIAA0777
Tested Applications
WB, IHC-P, IF, Flow
Physical Properties
Liquid

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