HEXA Antibody

• Background :

  HEXA is the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases.

• NCBI Gene ID :

  3073

• Swiss Prot :

  P06865

• Accession Number :

  P06865

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This HEXA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-343 amino acids from the Central region of human HEXA.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Neuroscience

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  61 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  HEXA

• NCBI Official Name :

  Beta-hexosaminidase subunit alpha

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Park, N.J., et.al., Pediatr. Res. (2009)

• Background Reference 02 :

  Pennybacker, M., et.al., J. Biol. Chem. 271 (29), 17377-17382 (1996)

• Other Product Names :

  Beta-hexosaminidase subunit alpha, Beta-N-acetylhexosaminidase subunit alpha, Hexosaminidase subunit A, N-acetyl-beta-glucosaminidase subunit alpha, HEXA

• Tested Applications :

  WB, IHC-P, Flow

• Protein ID :

  311033393

• Physical Properties :

  Liquid