CBFB Antibody

CAT: 0223-62-530Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-62-530Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2) . The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters.
NCBI Gene ID
865
Swiss Prot
Q13951
Accession Number
Q13951
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CBFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the Central region of human CBFB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
Rabbit Ig
Symbol
CBFB
NCBI Official Name
Core-binding factor subunit beta
NCBI Organism
Homo sapiens
Background Reference 01
Andersen, C.L., et.al., Br. J. Cancer 100 (3), 511-523 (2009)
Other Product Names
Core-binding factor subunit beta, CBF-beta, Polyomavirus enhancer-binding protein 2 beta subunit, PEA2-beta, PEBP2-beta, SL3-3 enhancer factor 1 subunit beta, SL3/AKV core-binding factor beta subunit, CBFB
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
2498753
Physical Properties
Liquid

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