CORIN Antibody

• Background:

  CORIN is a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. This protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.

• NCBI Gene ID:

  10699

• Swiss Prot:

  Q9Y5Q5

• Accession Number:

  Q9Y5Q5

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This CORIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 459-490 amino acids from the Central region of human CORIN.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  116 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CORIN

• NCBI Official Name:

  Atrial natriuretic peptide-converting enzyme

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Fox, A.A., et.al., Anesthesiology 110 (4), 738-747 (2009)

• Other Product Names:

  Atrial natriuretic peptide-converting enzyme, 3421-, Corin, Heart-specific serine proteinase ATC2, Pro-ANP-converting enzyme, Transmembrane protease serine 10, Atrial natriuretic peptide-converting enzyme, N-terminal propeptide, Atrial natriuretic peptide-converting enzyme, activated protease fragment, Atrial natriuretic peptide-converting enzyme, 180 kDa soluble fragment, Atrial natriuretic peptide-converting enzyme, 160 kDa soluble fragment, Atrial natriuretic peptide-converting enzyme, 100 kDa soluble fragment, CORIN, CRN, TMPRSS10

• Tested Applications:

  WB

• Protein ID:

  317373348

• Physical Properties:

  Liquid