MAPRE1 Antibody

CAT: 0223-62-452Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-62-452Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family.
NCBI Gene ID
22919
Swiss Prot
Q15691
Accession Number
Q15691
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This MAPRE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-71 amino acids from the N-terminal region of human MAPRE1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Rat, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
30 kDa
Fragment
Rabbit Ig
Symbol
MAPRE1
NCBI Official Name
Microtubule-associated protein RP/EB family member 1
NCBI Organism
Homo sapiens
Background Reference 01
Jaulin, F., et al. J. Cell Biol. 190 (3) :443-460 (2010)
Background Reference 02
Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 03
De Groot, C.O., et al. J. Biol. Chem. 285 (8) :5802-5814 (2010)
Background Reference 04
Jiang, K., et al. EMBO Rep. 10 (8) :857-865 (2009)
Other Product Names
Microtubule-associated protein RP/EB family member 1, APC-binding protein EB1, End-binding protein 1, EB1, MAPRE1
Tested Applications
WB, IHC-P, Flow
Protein ID
20138589
Physical Properties
Liquid

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