KYNU Antibody

• Background:

  KYNU is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. KYNU is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway.

• NCBI Gene ID:

  8942

• Swiss Prot:

  Q16719

• Accession Number:

  Q16719

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This KYNU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 359-386 amino acids from the C-terminal region of human KYNU.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  52 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  KYNU

• NCBI Official Name:

  Kynureninase {ECO:0000255|HAMAP-Rule:MF_03017}

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Christensen, M., et.al., J. Inherit. Metab. Dis. 30 (2), 248-255 (2007)

• Other Product Names:

  Kynureninase {ECO:0000255|HAMAP-Rule:MF_03017}, 3713 {ECO:0000255|HAMAP-Rule:MF_03017}, L-kynurenine hydrolase {ECO:0000255|HAMAP-Rule:MF_03017}, KYNU {ECO:0000255|HAMAP-Rule:MF_03017}

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  3913982

• Physical Properties:

  Liquid