TAGLN Antibody

• Background:

  TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear.

• NCBI Gene ID:

  6876

• Swiss Prot:

  Q01995

• Accession Number:

  Q01995

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This TAGLN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-167 amino acids from the C-terminal region of human TAGLN.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  23 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  TAGLN

• NCBI Official Name:

  Transgelin

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Zhao, L., Mod. Pathol. 22 (6), 786-796 (2009) Leguillette, R., Am. J. Respir. Crit. Care Med. 179 (3), 194-204 (2009) Yu, H., FASEB J. 22 (6), 1778-1789 (2008)

• Other Product Names:

  Transgelin, 22 kDa actin-binding protein, Protein WS3-10, Smooth muscle protein 22-alpha, SM22-alpha, TAGLN, SM22, WS3-10

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  3123283

• Physical Properties:

  Liquid