PLZF Antibody

• Background:

  PLZF is a member of the Krueppel C2H2-type zinc-finger protein family and a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL) .

• NCBI Gene ID:

  7704

• Swiss Prot:

  Q05516

• Accession Number:

  Q05516

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PLZF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 637-666 amino acids from the C-terminal region of human PLZF.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  74 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ZBTB16

• NCBI Official Name:

  Zinc finger and BTB domain-containing protein 16

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Shi, J., Int. J. Cancer 125 (7), 1558-1565 (2009)

• Background Reference 02:

  Doulatov, S., Genes Dev. 23 (17), 2076-2087 (2009)

• Other Product Names:

  Zinc finger and BTB domain-containing protein 16, Promyelocytic leukemia zinc finger protein, Zinc finger protein 145, Zinc finger protein PLZF, ZBTB16, PLZF, ZNF145

• Tested Applications:

  WB

• Protein ID:

  90109930

• Physical Properties:

  Liquid