NKRF Antibody

• Background:

  NKRF is a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.

• NCBI Gene ID:

  55922

• Swiss Prot:

  O15226

• Accession Number:

  O15226

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NKRF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-233 amino acids from the Central region of human NKRF.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  78 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  NKRF

• NCBI Official Name:

  NF-kappa-B-repressing factor

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ho, S.C., J. Immunol. 183 (1), 411-420 (2009)

• Background Reference 02:

  Glanz, A., Immunol. Cell Biol. 86 (7), 622-630 (2008)

• Other Product Names:

  NF-kappa-B-repressing factor, NFkB-repressing factor, Protein ITBA4, Transcription factor NRF, NKRF, ITBA4, NRF

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid