FGF18 Antibody

• Background :

  FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.

• NCBI Gene ID :

  8817

• Swiss Prot :

  O76093

• Accession Number :

  O76093

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This FGF18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-50 amino acids from the N-terminal region of human FGF18.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Mouse, Rat, Bovine

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  24 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:2000

• Symbol :

  FGF18

• NCBI Official Name :

  Fibroblast growth factor 18

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Wan, W.D., Beijing Da Xue Xue Bao 41 (4), 409-413 (2009)

• Background Reference 02 :

  Sonvilla, G., Carcinogenesis 29 (1), 15-24 (2008)

• Other Product Names :

  Fibroblast growth factor 18, FGF-18, zFGF5, FGF18

• Tested Applications :

  WB

• Physical Properties :

  Liquid