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FGF19 Antibody

CAT: 0223-59-730Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-730Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development.
NCBI Gene ID
9965
Swiss Prot
O95750
Accession Number
O95750
Host
Rabbit
Reactivity
Human
Immunogen
This FGF19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-202 amino acids from the C-terminal region of human FGF19.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
24 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
FGF19
NCBI Official Name
Fibroblast growth factor 19
NCBI Organism
Homo sapiens
Background Reference 01
Rao, A.S., et al. Gastroenterology 139 (5) :1549-1558 (2010)
Background Reference 02
Turnbull, C., et al. Nat. Genet. 42 (6) :504-507 (2010)
Background Reference 03
Schreuder, T.C., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 298 (3), G440-G445 (2010) :
Background Reference 04
Reiche, M., et al. Horm. Metab. Res. 42 (3) :178-181 (2010)
Other Product Names
Fibroblast growth factor 19, FGF-19, FGF19
Tested Applications
WB
Physical Properties
Liquid

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