FGF10 Antibody

• Background:

  The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.

• NCBI Gene ID:

  2255

• Swiss Prot:

  O15520

• Accession Number:

  O15520

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This FGF10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the C-terminal region of human FGF10.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  23 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  FGF10

• NCBI Official Name:

  Fibroblast growth factor 10

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Stein, J.L., et al. Neuroimage 53 (3) :1160-1174 (2010)

• Background Reference 02:

  Mostowska, A., et al. Birth Defects Res. PartClin. Mol. Teratol. 88 (7) :538-545 (2010)

• Background Reference 03:

  Chattopadhyay, I., et al. Mutat. Res. 696 (2) :130-138 (2010)

• Background Reference 04:

  Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

• Other Product Names:

  Fibroblast growth factor 10, FGF-10, Keratinocyte growth factor 2, FGF10

• Tested Applications:

  WB

• Physical Properties:

  Liquid