FGF10 Antibody

CAT: 0223-57-912Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-912Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.
NCBI Gene ID
2255
Swiss Prot
O15520
Accession Number
O15520
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This FGF10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the C-terminal region of human FGF10.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
23 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
FGF10
NCBI Official Name
Fibroblast growth factor 10
NCBI Organism
Homo sapiens
Background Reference 01
Stein, J.L., et al. Neuroimage 53 (3) :1160-1174 (2010)
Background Reference 02
Mostowska, A., et al. Birth Defects Res. PartClin. Mol. Teratol. 88 (7) :538-545 (2010)
Background Reference 03
Chattopadhyay, I., et al. Mutat. Res. 696 (2) :130-138 (2010)
Background Reference 04
Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Other Product Names
Fibroblast growth factor 10, FGF-10, Keratinocyte growth factor 2, FGF10
Tested Applications
WB
Physical Properties
Liquid

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