CALD1 Antibody

• Background:

  CALD1 is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca (2+) -calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca (2+) -dependent inhibition of smooth muscle contraction.

• NCBI Gene ID:

  800

• Swiss Prot:

  Q05682

• Accession Number:

  Q05682

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CALD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-457 amino acids from the Central region of human CALD1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  93 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CALD1

• NCBI Official Name:

  Caldesmon

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yoshio, T., FEBS Lett. 581 (20), 3777-3782 (2007) Mani, R.S., Biochemistry 31 (47), 11896-11901 (1992)

• Other Product Names:

  Caldesmon, CDM, CALD1, CAD, CDM

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  338817891

• Physical Properties:

  Liquid