Kallikrein 8 Antibody

• Background:

  Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. There are four different KLK8 isoforms, each exhibiting distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer.

• NCBI Gene ID:

  11202

• Swiss Prot:

  O60259

• Accession Number:

  O60259

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This Kallikrein 8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the Central region of human Kallikrein 8.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  28 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  KLK8

• NCBI Official Name:

  Kallikrein-8

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Li, Y., et al., Mol. Biol. Evol. 21 (11) :2111-2115 (2004) .

• Background Reference 02:

  Shigemasa, K., et al., Oncol. Rep. 11 (6) :1153-1159 (2004) .

• Background Reference 03:

  Cane, S., et al., Am. J. Obstet. Gynecol. 190 (1) :60-66 (2004) .

• Background Reference 04:

  Clark, H.F., et al., Genome Res. 13 (10) :2265-2270 (2003) .

• Other Product Names:

  Kallikrein-8, hK8, Neuropsin, NP, Ovasin, Serine protease 19, Serine protease TADG-14, Tumor-associated differentially expressed gene 14 protein, KLK8, NRPN, PRSS19, TADG14

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid