Kallikrein 5 Antibody

• Background:

  Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK5 expression is up-regulated by estrogens and progestins. The protein is secreted and may be involved in desquamation in the epidermis.

• NCBI Gene ID:

  25818

• Swiss Prot:

  Q9Y337

• Accession Number:

  Q9Y337

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This Kallikrein 5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-174 amino acids from the Central region of human Kallikrein 5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  32 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  KLK5

• NCBI Official Name:

  Kallikrein-5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Planque, C., et al., Biochem. Biophys. Res. Commun. 329 (4) :1260-1266 (2005) . Michael, I.P., et al., J. Biol. Chem. 280 (15) :14628-14635 (2005) . Ishida-Yamamoto, A., et al., J. Invest. Dermatol. 124 (2) :360-366 (2005) . Brattsand, M., et al., J. Invest. Dermatol. 124 (1) :198-203 (2005) . Caubet, C., et al., J. Invest. Dermatol. 122 (5) :1235-1244 (2004) .

• Other Product Names:

  Kallikrein-5, 3421-, Kallikrein-like protein 2, KLK-L2, Stratum corneum tryptic enzyme, KLK5, SCTE

• Tested Applications:

  WB

• Protein ID:

  296434569

• Physical Properties:

  Liquid