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ST5 Antibody

CAT: 0223-62-197Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-197Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ST5 was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells.
NCBI Gene ID
6764
Swiss Prot
P78524
Accession Number
P78524
Host
Rabbit
Reactivity
Human
Immunogen
This ST5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1106-1137 amino acids from the C-terminal region of human ST5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
126 kDa
Fragment
Rabbit Ig
Symbol
ST5
NCBI Official Name
Suppression of tumorigenicity 5 protein
NCBI Organism
Homo sapiens
Background Reference 01
Majidi, M., et al., J. Biol. Chem. 275 (9) :6560-6565 (2000) .
Background Reference 02
Hubbs, A.E., et al., Oncogene 18 (15) :2519-2525 (1999) .
Background Reference 03
Majidi, M., et al., J. Biol. Chem. 273 (26) :16608-16614 (1998) .
Background Reference 04
Lichy, J.H., et al., Nucleic Acids Res. 24 (23) :4700-4708 (1996) .
Other Product Names
Suppression of tumorigenicity 5 protein, DENN domain-containing protein 2B, HeLa tumor suppression 1, ST5, DENND2B, HTS1
Tested Applications
WB, Flow
Protein ID
317373507
Physical Properties
Liquid

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