CDX1 Antibody

• Background:

  This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity.

• NCBI Gene ID:

  1044

• Swiss Prot:

  P47902

• Accession Number:

  P47902

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CDX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-265 amino acids from the C-terminal region of human CDX1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  28 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CDX1

• NCBI Official Name:

  Homeobox protein CDX-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Domon-Dell, C., et al., Oncogene 22 (39) :7913-7921 (2003) .

• Background Reference 02:

  Suh, E.R., et al., J. Biol. Chem. 277 (39) :35795-35800 (2002) .

• Background Reference 03:

  Mizoshita, T., et al., Gastric Cancer 4 (4) :185-191 (2001) .

• Background Reference 04:

  Mallo, G.V., et al., Int. J. Cancer 74 (1) :35-44 (1997) .

• Other Product Names:

  Homeobox protein CDX-1, Caudal-type homeobox protein 1, CDX1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  116241291

• Physical Properties:

  Liquid