CDX4 Antibody

• Background:

  CDX are homeodomain transcription factors related to the Drosophila caudal gene. The vertebrate CDX have been implicated in the development of the posterior embryo. Several signaling molecules, notably retinoic acid (RA) and members of the Wnt (wingless) and fibroblast growth factor (FGF) families, are also implicated in patterning of the posterior vertebrate embryo. CDX family is the target of Wnt, RA and FGF signaling, suggesting that CDX factors act to convey the activity of these signaling molecules to Hox genes.

• NCBI Gene ID:

  1046

• Swiss Prot:

  O14627

• Accession Number:

  NP_005184

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDX4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CDX4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  30 kDa

• Applications Notes:

  CDX4 antibody can be used for detection of CDX4 by ELISA at 1:312500. CDX4 antibody can be used for detection of CDX4 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CDX4

• NCBI Official Name:

  Caudal type homeobox 4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Brian J. P. Huntly, et al., (2006) Proc Natl Acad Sci 103:16924.

• Other Product Names:

  CDX4

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  4885127

• Physical Properties:

  Liquid