HABP2 Antibody

• Background:

  HABP2 is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  3026

• Swiss Prot:

  Q14520

• Accession Number:

  Q14520

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This HABP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-408 amino acids from the C-terminal region of human HABP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  63 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  HABP2

• NCBI Official Name:

  Hyaluronan-binding protein 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Choi-Miura, N.H., et al. Biol. Pharm. Bull. 24 (2) :140-143 (2001)

• Background Reference 02:

  Sumiya, J., et al. J. Biochem. 122 (5) :983-990 (1997)

• Background Reference 03:

  Choi-Miura, N.H., et al. J. Biochem. 119 (6) :1157-1165 (1996)

• Background Reference 04:

  Gupta, S., et al. Eur. J. Cell Biol. 56 (1) :58-67 (1991)

• Other Product Names:

  Hyaluronan-binding protein 2, 3421-, Factor VII-activating protease, Factor seven-activating protease, FSAP, Hepatocyte growth factor activator-like protein, Plasma hyaluronan-binding protein, Hyaluronan-binding protein 2 50 kDa heavy chain, Hyaluronan-binding protein 2 50 kDa heavy chain alternate form, Hyaluronan-binding protein 2 27 kDa light chain, Hyaluronan-binding protein 2 27 kDa light chain alternate form, HABP2, HGFAL, PHBP

• Tested Applications:

  WB, IHC-P

• Protein ID:

  73919921

• Physical Properties:

  Liquid