EID2 Antibody

• Background:

  EID2 interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. It may act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.

• NCBI Gene ID:

  163126

• Swiss Prot:

  Q8N6I1

• Accession Number:

  Q8N6I1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This EID2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-208 amino acids from the C-terminal region of human EID2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  25 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  EID2

• NCBI Official Name:

  EP300-interacting inhibitor of differentiation 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lee, H.J., et al. J. Biol. Chem. 279 (4) :2666-2672 (2004)

• Background Reference 02:

  Ji, A., et al. Gene 318, 35-43 (2003) :

• Other Product Names:

  EP300-interacting inhibitor of differentiation 2, EID-2, CREBBP/EP300 inhibitor 2, EID-1-like inhibitor of differentiation 2, EID2 {ECO:0000312|EMBL:AAH301373}

• Tested Applications:

  WB

• Protein ID:

  74762532

• Physical Properties:

  Liquid