EID2 Antibody

• Background :

  EID2 interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. It may act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.

• NCBI Gene ID :

  163126

• Swiss Prot :

  Q8N6I1

• Accession Number :

  Q8N6I1

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This EID2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-208 amino acids from the C-terminal region of human EID2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  25 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  EID2

• NCBI Official Name :

  EP300-interacting inhibitor of differentiation 2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Lee, H.J., et al. J. Biol. Chem. 279 (4) :2666-2672 (2004)

• Background Reference 02 :

  Ji, A., et al. Gene 318, 35-43 (2003) :

• Other Product Names :

  EP300-interacting inhibitor of differentiation 2, EID-2, CREBBP/EP300 inhibitor 2, EID-1-like inhibitor of differentiation 2, EID2 {ECO:0000312|EMBL:AAH301373}

• Tested Applications :

  WB

• Protein ID :

  74762532

• Physical Properties :

  Liquid