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BDHA1 Antibody

CAT: 0223-61-972Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-61-972Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO (2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) . The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex.
NCBI Gene ID
5160
Swiss Prot
P08559
Accession Number
P08559
Host
Rabbit
Reactivity
Human
Immunogen
This BDHA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-255 amino acids from the Central region of human BDHA1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
43 kDa
Fragment
Rabbit Ig
Symbol
PDHA1
NCBI Official Name
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Glushakova, L.G., et al. Mol. Genet. Metab. 98 (3) :289-299 (2009)
Background Reference 02
Joao Silva, M., et al. Eur. J. Pediatr. 168 (1) :17-22 (2009)
Background Reference 03
Boichard, A., et al. Mol. Genet. Metab. 93 (3) :323-330 (2008)
Other Product Names
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial, PDHE1-A type I, PDHA1, PHE1A
Tested Applications
WB, Flow
Protein ID
129063
Physical Properties
Liquid

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