PTAFR Antibody

CAT: 0223-61-919Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-61-919Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PTAFR shows structural characteristics of the rhodopsin (MIM 180380) gene family and binds platelet-activating factor (PAF) . PAF is a phospholipid (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.
NCBI Gene ID
5724
Swiss Prot
P25105
Accession Number
P25105
Host
Rabbit
Reactivity
Human
Immunogen
This PTAFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-312 amino acids from the C-terminal region of human PTAFR.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PTAFR
NCBI Official Name
Platelet-activating factor receptor
NCBI Organism
Homo sapiens
Background Reference 01
Davila, S., et al. Genes Immun. (2010) In press :
Background Reference 02
Hirota, N., et al. J. Biol. Chem. 285 (8) :5931-5940 (2010)
Background Reference 03
Kaneko, K., et al. J. Invest. Dermatol. 129 (11) :2567-2573 (2009)
Background Reference 04
Melnikova, V.O., et al. J. Biol. Chem. 284 (42) :28845-28855 (2009)
Other Product Names
Platelet-activating factor receptor, PAF-R, PAFr, PTAFR, PAFR
Tested Applications
WB
Protein ID
129557
Physical Properties
Liquid

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