PTAFR Antibody

• Background:

  PTAFR shows structural characteristics of the rhodopsin (MIM 180380) gene family and binds platelet-activating factor (PAF) . PAF is a phospholipid (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.

• NCBI Gene ID:

  5724

• Swiss Prot:

  P25105

• Accession Number:

  P25105

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PTAFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-312 amino acids from the C-terminal region of human PTAFR.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction, Growth Factors

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  39 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PTAFR

• NCBI Official Name:

  Platelet-activating factor receptor

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Davila, S., et al. Genes Immun. (2010) In press :

• Background Reference 02:

  Hirota, N., et al. J. Biol. Chem. 285 (8) :5931-5940 (2010)

• Background Reference 03:

  Kaneko, K., et al. J. Invest. Dermatol. 129 (11) :2567-2573 (2009)

• Background Reference 04:

  Melnikova, V.O., et al. J. Biol. Chem. 284 (42) :28845-28855 (2009)

• Other Product Names:

  Platelet-activating factor receptor, PAF-R, PAFr, PTAFR, PAFR

• Tested Applications:

  WB

• Protein ID:

  129557

• Physical Properties:

  Liquid