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FADS2 Antibody

CAT: 0223-61-904Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-61-904Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.
NCBI Gene ID
9415
Swiss Prot
O95864
Accession Number
O95864
Host
Rabbit
Reactivity
Human
Immunogen
This FADS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-122 amino acids from the Central region of human FADS2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
52 kDa
Fragment
Rabbit Ig
Symbol
FADS2
NCBI Official Name
Fatty acid desaturase 2
NCBI Organism
Homo sapiens
Background Reference 01
Molto-Puigmarti, C., et al. Am. J. Clin. Nutr. (2010) In press :
Background Reference 02
Lattka, E., et al. Curr. Opin. Lipidol. 21 (1) :64-69 (2010)
Background Reference 03
Lattka, E., et al. J. Lipid Res. 51 (1) :182-191 (2010)
Background Reference 04
Glaser, C., et al. Metab. Clin. Exp. (2009) In press :
Other Product Names
Fatty acid desaturase 2, 11419-, Delta (6) fatty acid desaturase, D6D, Delta (6) desaturase, Delta-6 desaturase, FADS2
Tested Applications
WB, IHC-P, Flow
Physical Properties
Liquid

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