FADS3 Antibody

• Background:

  The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.

• NCBI Gene ID:

  3995

• Swiss Prot:

  Q9Y5Q0

• Accession Number:

  Q9Y5Q0

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This FADS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 328-355 amino acids from the C-terminal region of human FADS3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  51 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  FADS3

• NCBI Official Name:

  Fatty acid desaturase 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02:

  Mathias, R.A., et al. J. Lipid Res. 51 (9) :2766-2774 (2010)

• Background Reference 03:

  Barber, M.J., et al. PLoS ONE (3), E9763 (2010) :

• Background Reference 04:

  Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

• Other Product Names:

  Fatty acid desaturase 3, 11419-, Cytochrome b5-related protein, FADS3, CYB5RP

• Tested Applications:

  WB

• Protein ID:

  74762790

• Physical Properties:

  Liquid