UBAC1 Antibody

• Background:

  UBAC1 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein has two RRM domains that bind to RNAs.

• NCBI Gene ID:

  10422

• Swiss Prot:

  Q9BSL1

• Accession Number:

  Q9BSL1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This UBAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-292 amino acids from the C-terminal region of human UBAC1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  45 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  UBAC1

• NCBI Official Name:

  Ubiquitin-associated domain-containing protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Walker, L.C., et al. Breast Cancer Res. Treat. 112 (2) :229-236 (2008)

• Background Reference 02:

  Wu, Y.Y., et al. Cell Biochem. Funct. 26 (4) :467-477 (2008)

• Background Reference 03:

  Reboll, M.R., et al. RNA 13 (8) :1328-1340 (2007)

• Other Product Names:

  Ubiquitin-associated domain-containing protein 1, UBA domain-containing protein 1, E3 ubiquitin-protein ligase subunit KPC2, Glialblastoma cell differentiation-related protein 1, Kip1 ubiquitination-promoting complex protein 2, UBAC1, GBDR1, KPC2, UBADC1

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  74752306

• Physical Properties:

  Liquid