KLC3 Antibody

• Background:

  KLC3 encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.

• NCBI Gene ID:

  147700

• Swiss Prot:

  Q6P597

• Accession Number:

  Q6P597

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This KLC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-274 amino acids from the Central region of human KLC3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  55 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  KLC3

• NCBI Official Name:

  Kinesin light chain 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Zhang, Y., et al. Dev. Biol. 275 (1) :23-33 (2004)

• Background Reference 02:

  Bhullar, B., et al. J. Biol. Chem. 278 (18) :16159-16168 (2003)

• Background Reference 03:

  Junco, A., et al. Biol. Reprod. 64 (5) :1320-1330 (2001)

• Other Product Names:

  Kinesin light chain 3, KLC2-like, kinesin light chain 2, KLC3, KLC2, KLC2L

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  91207086

• Physical Properties:

  Liquid