ASB15 Antibody

• Background:

  ASB15 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

• NCBI Gene ID:

  142685

• Swiss Prot:

  Q8WXK1

• Accession Number:

  Q8WXK1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This ASB15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-287 amino acids from the Central region of human ASB15.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  66 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ASB15

• NCBI Official Name:

  Ankyrin repeat and SOCS box protein 15

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Szafranski, K., et al. Genome Biol. (8), R154 (2007)

• Background Reference 02:

  Kohroki, J., et al. FEBS Lett. 579 (30) :6796-6802 (2005)

• Background Reference 03:

  Yoshida, K. Int. J. Mol. Med. 16 (2) :343-347 (2005)

• Other Product Names:

  Ankyrin repeat and SOCS box protein 15, ASB-15, ASB15

• Tested Applications:

  WB

• Protein ID:

  296439431

• Physical Properties:

  Liquid