UBXN6 Antibody

• Background:

  UBXN6 acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. UBXN6 is MDM2 stabilization leads to MDM2-dependent TP53 degradation.

• NCBI Gene ID:

  80700

• Swiss Prot:

  Q9BZV1

• Accession Number:

  Q9BZV1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This UBXN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-309 amino acids from the C-terminal region of human UBXN6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  50 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  UBXN6

• NCBI Official Name:

  UBX domain-containing protein 6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Nagahama, M., et al. Biochem. Biophys. Res. Commun. 382 (2) :303-308 (2009)

• Background Reference 02:

  Kern, M., et al. Biochem. Biophys. Res. Commun. 380 (2) :303-307 (2009)

• Background Reference 03:

  Madsen, L., et al. Int. J. Biochem. Cell Biol. 40 (12) :2927-2942 (2008)

• Other Product Names:

  UBX domain-containing protein 6, UBX domain-containing protein 1, UBXN6, UBXD1, UBXDC2

• Tested Applications:

  WB, IHC-P

• Protein ID:

  30913412

• Physical Properties:

  Liquid