APITD1 Antibody

• Background:

  APITD1 was identified in the neuroblastoma tumour suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF (II) 31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumours, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway.

• NCBI Gene ID:

  100526739378708

• Swiss Prot:

  Q8N2Z9

• Accession Number:

  Q8N2Z9

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This APITD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-74 amino acids from the Central region of human APITD1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  16 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  APITD1

• NCBI Official Name:

  Centromere protein S

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Amano, M., et al. J. Cell Biol. 186 (2) :173-182 (2009)

• Background Reference 02:

  Van Gils, W., et al. Invest. Ophthalmol. Vis. Sci. 48 (11) :4919-4923 (2007)

• Background Reference 03:

  Okada, M., et al. Nat. Cell Biol. 8 (5) :446-457 (2006)

• Other Product Names:

  Centromere protein S, CENP-S, Apoptosis-inducing TAF9-like domain-containing protein 1, FANCM-interacting histone fold protein 1, Fanconi anemia-associated polypeptide of 16 kDa, APITD1, CENPS, FAAP16, MHF1

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  74759833

• Physical Properties:

  Liquid