OPN1MW Antibody

• Background:

  OPN1MW encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness.

• NCBI Gene ID:

  1010602332652720000

• Swiss Prot:

  P04001

• Accession Number:

  P04001

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This OPN1MW antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human OPN1MW.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction, Growth Factors

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat, Chicken, Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  41 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  OPN1MW

• NCBI Official Name:

  Medium-wave-sensitive opsin 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Thirumuruganandham, S.P., et al.Mol Model 15 (8) :959-969 (2009)

• Background Reference 02:

  Ala-Laurila, P., et al. J. Biol. Chem. 284 (24) :16492-16500 (2009)

• Background Reference 03:

  Holmes, M.V., et al. PLoS ONE (12), E7960 (2009)

• Other Product Names:

  Medium-wave-sensitive opsin 1, Green cone photoreceptor pigment, Green-sensitive opsin, GOP, OPN1MW, GCP

• Tested Applications:

  WB, Flow

• Protein ID:

  129215

• Physical Properties:

  Liquid