NASP Antibody

• Background:

  NASP encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.

• NCBI Gene ID:

  4678

• Swiss Prot:

  P49321

• Accession Number:

  P49321

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NASP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the N-terminal region of human NASP.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  85 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  NASP

• NCBI Official Name:

  Nuclear autoantigenic sperm protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Alekseev, O.M., et al. Reprod. Biol. Endocrinol. 7, 45 (2009)

• Background Reference 02:

  Wang, H., et al. Nucleic Acids Res. 36 (18) :5763-5772 (2008)

• Background Reference 03:

  Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

• Other Product Names:

  Nuclear autoantigenic sperm protein, NASP, NASP

• Tested Applications:

  WB, Flow

• Protein ID:

  23503077

• Physical Properties:

  Liquid