FA2H Antibody

• Background:

  FA2H is a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups.

• NCBI Gene ID:

  79152

• Swiss Prot:

  Q7L5A8

• Accession Number:

  Q7L5A8

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This FA2H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-148 amino acids from the Central region of human FA2H.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  FA2H

• NCBI Official Name:

  Fatty acid 2-hydroxylase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wheeler, H.E., et al. PLoS Genet. (10), E1000685 (2009)

• Background Reference 02:

  Edvardson, S., et al. Am. J. Hum. Genet. 83 (5) :643-648 (2008)

• Background Reference 03:

  Uchida, Y., et al. J. Biol. Chem. 282 (18) :13211-13219 (2007)

• Other Product Names:

  Fatty acid 2-hydroxylase, 1---, Fatty acid alpha-hydroxylase, FA2H, FAAH

• Tested Applications:

  WB, IHC-P

• Protein ID:

  74749893

• Physical Properties:

  Liquid