S47A2 Antibody

• Background:

  S47A2 belongs to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17.

• NCBI Gene ID:

  146802

• Swiss Prot:

  Q86VL8

• Accession Number:

  Q86VL8

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This S47A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-153 amino acids from the N-terminal region of human S47A2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  65 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SLC47A2

• NCBI Official Name:

  Multidrug and toxin extrusion protein 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Toyama, K., et al. Pharmacogenet. Genomics 20 (2) :135-138 (2010)

• Background Reference 02:

  Kajiwara, M., et al. J. Hum. Genet. 54 (1) :40-46 (2009)

• Background Reference 03:

  Ohta, K.Y., et al.Pharm Pharm Sci 12 (3) :388-396 (2009)

• Other Product Names:

  Multidrug and toxin extrusion protein 2, MATE-2, hMATE-2, Kidney-specific H (+) /organic cation antiporter, Solute carrier family 47 member 2, SLC47A2, MATE2

• Tested Applications:

  WB

• Protein ID:

  74727585

• Physical Properties:

  Liquid