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ABL Antibody

CAT: 0223-61-626Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-61-626Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ABL2 is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. The peptide used to generate this antibody is 100% conserved between ABL2 and ABL1.
NCBI Gene ID
25
Swiss Prot
P00519
Accession Number
P00519
Host
Rabbit
Reactivity
Human
Immunogen
This ABL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y251 of human ABL.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
123 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ABL1
NCBI Official Name
Tyrosine-protein kinase ABL1
NCBI Organism
Homo sapiens
Background Reference 01
Cao, C., et al., Biochemistry 42 (35) :10348-10353 (2003) .
Background Reference 02
Cao, C., et al., J. Biol. Chem. 278 (32) :29667-29675 (2003) .
Background Reference 03
Kruh, G.D., et al., Proc. Natl. Acad. Sci. U.S.A. 87 (15) :5802-5806 (1990) .
Background Reference 04
Kruh, G.D., et al., Science 234 (4783) :1545-1548 (1986) .
Other Product Names
Abelson tyrosine-protein kinase 2, Abelson murine leukemia viral oncogene homolog 2, Abelson-related gene protein, Tyrosine-protein kinase ARG, ABL2, ABLL, ARG
Tested Applications
WB
Protein ID
85681908
Physical Properties
Liquid

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