SNRPB Antibody

• Background:

  SNRPB is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs) . These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein.

• NCBI Gene ID:

  6628

• Swiss Prot:

  P14678

• Accession Number:

  P14678

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SNRPB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-65 amino acids from the N-terminal region of human SNRPB.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  25 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SNRPB

• NCBI Official Name:

  Small nuclear ribonucleoprotein-associated proteins B and B'

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Elkon, K.B., et.al., J. Immunol. 145 (2), 636-643 (1990)

• Background Reference 02:

  Chu, J.L. et.al., Gene 97 (2), 311-312 (1991)

• Other Product Names:

  Small nuclear ribonucleoprotein-associated proteins B and B', snRNP-B, Sm protein B/B', Sm-B/B', SmB/B', SNRPB, COD, SNRPB1

• Tested Applications:

  WB, Flow

• Protein ID:

  134037

• Physical Properties:

  Liquid