Products for Research Use Only

SNRPB Antibody

CAT: 0223-61-624Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-61-624Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SNRPB is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs) . These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein.
NCBI Gene ID
6628
Swiss Prot
P14678
Accession Number
P14678
Host
Rabbit
Reactivity
Human
Immunogen
This SNRPB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-65 amino acids from the N-terminal region of human SNRPB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
25 kDa
Fragment
Rabbit Ig
Symbol
SNRPB
NCBI Official Name
Small nuclear ribonucleoprotein-associated proteins B and B'
NCBI Organism
Homo sapiens
Background Reference 01
Elkon, K.B., et.al., J. Immunol. 145 (2), 636-643 (1990)
Background Reference 02
Chu, J.L. et.al., Gene 97 (2), 311-312 (1991)
Other Product Names
Small nuclear ribonucleoprotein-associated proteins B and B', snRNP-B, Sm protein B/B', Sm-B/B', SmB/B', SNRPB, COD, SNRPB1
Tested Applications
WB, Flow
Protein ID
134037
Physical Properties
Liquid