SNRPA Antibody

• Background:

  The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.

• NCBI Gene ID:

  6626

• Swiss Prot:

  P09012

• Accession Number:

  P09012

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SNRPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-111 amino acids from the Central region of human SNRPA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Pig

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  31 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SNRPA

• NCBI Official Name:

  U1 small nuclear ribonucleoprotein A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Guan, F., et al. RNA 13 (12) :2129-2140 (2007)

• Background Reference 02:

  Hall-Pogar, T., et al. RNA 13 (7) :1103-1115 (2007)

• Background Reference 03:

  Shajani, Z., et al. J. Mol. Biol. 349 (4) :699-715 (2005)

• Background Reference 04:

  Andersen, J.S., et al. Nature 433 (7021) :77-83 (2005)

• Other Product Names:

  U1 small nuclear ribonucleoprotein A, U1 snRNP A, U1-A, U1A, SNRPA

• Tested Applications:

  WB, IHC-P

• Protein ID:

  134092

• Physical Properties:

  Liquid