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SNRPN Antibody

CAT: 0223-8155-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-8155-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The small nuclear riboprotein-associated protein N (SNRPN) is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. SNRPN plays a role in pre-mRNA processing and alternative splicing (1) . SNRPN arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF) (2) . Mutations or deletions in the SNRPN gene may be linked to responsible for Angelman syndrome or Prader-Willi syndrome (3) .
NCBI Gene ID
6638
Swiss Prot
P63164
Accession Number
NP_003088
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
SNRPN antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1208 - THP-1 Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (100%), Chicken: (95%)
Buffer
SNRPN antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
SNRPN antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
SNRPN antibody is human, mouse and rat reactive.
Symbol
SNRPN
Positive Control 2
Cat. No. 10-901 - Human Spleen Tissue Slide
NCBI Official Name
Small nuclear ribonucleoprotein polypeptide N
NCBI Organism
Homo sapiens
Background Reference 01
Ozcelik T, Leff S, Robinson W, et al. Small nuclear ribonucleoprotein polypeptide N (SNRPN), an expressed gene in the Prader-Willi syndrome critical region. Nat. Genet. 1992; 2:265-9.
Background Reference 02
Gray TA, Saitoh S, and Nicholls RD. An imprinted, mammalian bicistronic transcript encodes two independent proteins. Proc. Natl. Acad. Sci. USA 1999; 96:5616-21.
Background Reference 03
Chen Y, Liu YJ, Pei YF, et al. Copy number variations at the Prader-Willi syndrome region on chromosome 15 and associations with obesity in whites. Obesity 2011; 19:1229-34.
Other Product Names
Small nuclear ribonucleoprotein-associated protein N, HCERN3, PWCR, RT-LI, SM-D, SMN, SNRNP-N, SNURF-SNRPN, sm-N
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
4507135
Physical Properties
Liquid

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