CD138 Antibody

• Background:

  CD138 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins.

• NCBI Gene ID:

  6382

• Swiss Prot:

  P18827

• Accession Number:

  P18827

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CD138 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-295 amino acids from the C-terminal region of human CD138.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Neuroscience, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  32 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SDC1

• NCBI Official Name:

  Syndecan-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rikova, K., et.al., Cell 131 (6), 1190-1203 (2007)

• Background Reference 02:

  Endo, K., et.al., J. Biol. Chem. 278 (42), 40764-40770 (2003)

• Other Product Names:

  Syndecan-1, SYND1, CD138, SDC1, SDC

• Tested Applications:

  WB

• Protein ID:

  229463011

• Physical Properties:

  Liquid