IMMT Antibody

CAT: 0223-61-609Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-61-609Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mitochondria are the center of cellular energy production and essential metabolic reactions. As double membrane-bound organelles, mitochondria from different species, tissues, and metabolic states are highly polymorphic in nature, yet exhibit common structural features. The ultrastructural variations in mitochondrial architecture occur mainly due to the differences in the amount and shape of cristae. Abundant cristae are found in mitochondria from tissues where energy demand is high. Analysis of the human heart mitochondrial proteome shows that mitofilin is one of the most abundant mitochondrial proteins. It appears to play an important role in the maintenance of cristae morphology.
NCBI Gene ID
10989
Swiss Prot
Q16891
Accession Number
Q16891
Host
Rabbit
Reactivity
Human
Immunogen
This IMMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-467 amino acids from the Central region of human IMMT.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
84 kDa
Fragment
Rabbit Ig
Symbol
IMMT
NCBI Official Name
MICOS complex subunit MIC60
NCBI Organism
Homo sapiens
Background Reference 01
Bernert, G., et.al., Proteomics (12), 1752-1757 (2002)
Other Product Names
MICOS complex subunit MIC60, Cell proliferation-inducing gene 4/52 protein, Mitochondrial inner membrane protein, Mitofilin, p87/89, IMMT, HMP, MIC60, MINOS2
Tested Applications
WB, IHC-P, Flow
Protein ID
29427676
Physical Properties
Liquid

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