APRT Antibody

• Background :

  A conserved feature of APRT is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP) . It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.

• NCBI Gene ID :

  353

• Swiss Prot :

  P07741

• Accession Number :

  P07741

• Host :

  Rabbit

• Reactivity :

  Human, Rat

• Immunogen :

  This APRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-170 amino acids from the C-terminal region of human APRT.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Obesity, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  20 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  APRT

• NCBI Official Name :

  Adenine phosphoribosyltransferase

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Silva, C.H., et. al., J. Biomol. Struct. Dyn. 25 (6), 589-597 (2008)

• Background Reference 02 :

  Di Pietro, V., et. al., Clin. Biochem. 40 (1-2), 73-80 (2007)

• Other Product Names :

  Adenine phosphoribosyltransferase, APRT, APRT

• Tested Applications :

  WB, IHC-P

• Protein ID :

  114074

• Physical Properties :

  Liquid