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M6PR Antibody

CAT: 0223-61-508Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-61-508Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.
NCBI Gene ID
4074
Swiss Prot
P20645
Accession Number
P20645
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This M6PR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-63 amino acids from the N-terminal region of human M6PR.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
31 kDa
Fragment
Rabbit Ig
Symbol
M6PR
NCBI Official Name
Cation-dependent mannose-6-phosphate receptor
NCBI Organism
Homo sapiens
Background Reference 01
Perez-Victoria, F.J., Mol. Biol. Cell 19 (6), 2350-2362 (2008)
Background Reference 02
Mari, M., Traffic (3), 380-393 (2008)
Background Reference 03
Lemansky, P., J. Leukoc. Biol. 81 (4), 1149-1158 (2007)
Background Reference 04
Chen, J.J., Cell 119 (7), 915-926 (2004)
Other Product Names
Cation-dependent mannose-6-phosphate receptor, CD Man-6-P receptor, CD-MPR, 46 kDa mannose 6-phosphate receptor, MPR 46, M6PR, MPR46, MPRD
Tested Applications
WB, IHC-P
Protein ID
127293
Physical Properties
Liquid

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MBS9415826-01M6PR Antibody

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