EXOSC8 Antibody

• Background :

  EXOSC8 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. It is required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and has a 3'-5' exonuclease activity.

• NCBI Gene ID :

  11340

• Swiss Prot :

  Q96B26

• Accession Number :

  Q96B26

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This EXOSC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-276 amino acids from the C-terminal region of human EXOSC8.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  30 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  EXOSC8

• NCBI Official Name :

  Exosome complex component RRP43

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Raijmakers, R., J. Mol. Biol. 323 (4), 653-663 (2002)

• Background Reference 02 :

  Jiang, T., Proc. Natl. Acad. Sci. U.S.A. 99 (8), 5295-5300 (2002)

• Background Reference 03 :

  Raijmakers, R., J. Mol. Biol. 315 (4), 809-818 (2002)

• Background Reference 04 :

  Brouwer, R., J. Biol. Chem. 276 (9), 6177-6184 (2001)

• Other Product Names :

  Exosome complex component RRP43, Exosome component 8, Opa-interacting protein 2, OIP-2, Ribosomal RNA-processing protein 43, p9, EXOSC8, OIP2, RRP43

• Tested Applications :

  WB, IHC-P, Flow

• Protein ID :

  21759409

• Physical Properties :

  Liquid