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HNF4A Antibody

CAT: 0223-61-499Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-61-499Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HNF4A is a nuclear transcription factor which binds DNA as a homodimer. This protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This protein may play a role in development of the liver, kidney, and intestines. Mutations in this protein have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I.
NCBI Gene ID
3172
Swiss Prot
P41235
Accession Number
P41235
Host
Rabbit
Reactivity
Human
Immunogen
This HNF4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-146 amino acids from human HNF4A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Cell Cycle, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
53 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HNF4A
NCBI Official Name
Hepatocyte nuclear factor 4-alpha
NCBI Organism
Homo sapiens
Background Reference 01
Sugai, M., Pathol. Int. 58 (11), 681-686 (2008)
Background Reference 02
Lee, S.S., Hepatology 48 (2), 635-645 (2008)
Background Reference 03
Guo, H., Biochem. J. 394 (PT 2), 379-387 (2006)
Background Reference 04
Hong, Y.H., J. Biol. Chem. 278 (30), 27495-27501 (2003)
Other Product Names
Hepatocyte nuclear factor 4-alpha, HNF-4-alpha, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, TCF-14, Transcription factor HNF-4, HNF4A, HNF4, NR2A1, TCF14
Tested Applications
WB
Protein ID
148886624
Physical Properties
Liquid

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