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MGST1 Antibody

CAT: 0223-61-481Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-61-481Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds.This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress.
NCBI Gene ID
4257
Swiss Prot
P10620
Accession Number
P10620
Host
Rabbit
Reactivity
Human
Immunogen
This MGST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-71 amino acids from the Central region of human MGST1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Cell Cycle, Obesity
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
18 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:4000
Symbol
MGST1
NCBI Official Name
Microsomal glutathione S-transferase 1
NCBI Organism
Homo sapiens
Background Reference 01
Zhang, H., IntColorectal Dis 22 (10), 1185-1194 (2007)
Background Reference 02
Prall, W.C., Mech. Ageing Dev. 128 (9), 503-510 (2007)
Background Reference 03
Haines, J.L., Invest. Ophthalmol. Vis. Sci. 47 (1), 329-335 (2006)
Other Product Names
Microsomal glutathione S-transferase 1, Microsomal GST-1, Microsomal GST-I, MGST1, GST12, MGST
Tested Applications
WB
Protein ID
121740
Physical Properties
Liquid

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