INDO Antibody

• Background:

  Gamma-interferon (IFNG; MIM 147570) has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and Chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase (INDO; EC 1.13.11.52) . This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine.[supplied by OMIM]

• NCBI Gene ID:

  3620

• Swiss Prot:

  P14902

• Accession Number:

  P14902

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This INDO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-403 amino acids from the C-terminal region of human INDO.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  45 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  IDO1

• NCBI Official Name:

  Indoleamine 2,3-dioxygenase 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Maghzal, G.J., J. Biol. Chem. 283 (18), 12014-12025 (2008)

• Background Reference 02:

  Chauhan, N., Biochemistry 47 (16), 4761-4769 (2008)

• Background Reference 03:

  Scheler, M., Am. J. Pathol. 171 (6), 1936-1943 (2007)

• Other Product Names:

  Indoleamine 2,3-dioxygenase 1, IDO-1, Indoleamine-pyrrole 2,3-dioxygenase, IDO1, IDO, INDO

• Tested Applications:

  WB, IHC-P

• Protein ID:

  123948

• Physical Properties:

  Liquid