INDO Antibody

CAT: 0223-61-459Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-61-459Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Gamma-interferon (IFNG; MIM 147570) has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and Chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase (INDO; EC 1.13.11.52) . This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine.[supplied by OMIM]
NCBI Gene ID
3620
Swiss Prot
P14902
Accession Number
P14902
Host
Rabbit
Reactivity
Human
Immunogen
This INDO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-403 amino acids from the C-terminal region of human INDO.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
45 kDa
Fragment
Rabbit Ig
Symbol
IDO1
NCBI Official Name
Indoleamine 2,3-dioxygenase 1
NCBI Organism
Homo sapiens
Background Reference 01
Maghzal, G.J., J. Biol. Chem. 283 (18), 12014-12025 (2008)
Background Reference 02
Chauhan, N., Biochemistry 47 (16), 4761-4769 (2008)
Background Reference 03
Scheler, M., Am. J. Pathol. 171 (6), 1936-1943 (2007)
Other Product Names
Indoleamine 2,3-dioxygenase 1, IDO-1, Indoleamine-pyrrole 2,3-dioxygenase, IDO1, IDO, INDO
Tested Applications
WB, IHC-P
Protein ID
123948
Physical Properties
Liquid

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