Aldolase Antibody

• Background:

  Aldolase A (fructose-bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia.

• NCBI Gene ID:

  226

• Swiss Prot:

  P04075

• Accession Number:

  P04075

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This Aldolase (ALDOA) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-95 amino acids from the N-terminal region of human Aldolase (ALDOA) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  39 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ALDOA

• NCBI Official Name:

  Fructose-bisphosphate aldolase A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Gizak, A., Proteins 72 (1), 209-216 (2008)

• Background Reference 02:

  Lu, J., Biochem. Biophys. Res. Commun. 369 (3), 948-952 (2008)

• Background Reference 03:

  Valis, K., Mol. Cell. Biochem. 311 (1-2), 225-231 (2008)

• Other Product Names:

  Fructose-bisphosphate aldolase A, Lung cancer antigen NY-LU-1, Muscle-type aldolase, ALDOA, ALDA

• Tested Applications:

  WB, IHC-P, IF

• Protein ID:

  113606

• Physical Properties:

  Liquid