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BCDIN3D Antibody

CAT: 0223-61-351Size: 200 µLDry Ice: NoHazardous: No
CAT#:0223-61-351Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
O-methyltransferase that specifically dimethylates the 5' monophosphate of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Able to mediate methylation of pre-miR-145, as well as other pre- miRNAs.
NCBI Gene ID
144233
Swiss Prot
Q7Z5W3
Accession Number
Q7Z5W3
Host
Rabbit
Reactivity
Human
Immunogen
This BCDIN3D antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 243-276 amino acids from human BCDIN3D.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000-2000
Symbol
BCDIN3D
NCBI Official Name
Pre-miRNA 5'-monophosphate methyltransferase
NCBI Organism
Homo sapiens
Background Reference 01
Ota T., et al.Nat. Genet. 36:40-45 (2004) .
Background Reference 02
Mural R.J., et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Background Reference 03
Xhemalce B., et al.Cell 151:278-288 (2012) .
Other Product Names
Pre-miRNA 5'-monophosphate methyltransferase, 2.1.1.-, BCDIN3 domain-containing protein, BCDIN3D
Tested Applications
WB
Protein ID
74738762
Physical Properties
Liquid

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